RMB - move forward/accelerate
LMB - move backward/hover/decelerate
D zoom in weapon / weapon switch in the gunship
F fire
C prone
V crouch
T reload
A sprint/boost
Z/X strafe left/right
Q/W comm. rose 1/2
E enter/exit vehicle
R jump
Umm... that about covers the basics.
It's kind of an inverse idea of the regular WASD setup - movement is moved to Z/X and the mouse buttons...
I play all my shooters like this, with light modifications depending on game of course, but generally Z/X strafe, F fire, R/V jump/crouch, T reload, D or G weapon zoom, A sprint etc.
My fingers usually rest on the azxf<spacebar> keys and I move them for the other functions. I don't think I ever use my thumb actually... except for seat switching. Seat-switching in 2142 is f2,d,f,f1, which for me is index, thumb, thumb, middle... kind of strange for most but my hands are used to it pretty well now.
Personally, I don't know why the WASD setup is so popular. I think you lose some accuracy by pressing the mouse button, as opposed to F on the keyboard... but then again, I like Verdun too lol.